Carboxylic acid salts
Apexbio Technology LLC CX-4945 sodium salt 1309357-15-0 5mg
CX-4945 sodium salt (Silmitasertib sodium salt CAS 1309357-15-0) is a potent and selective inhibitor of casein kinase 2 (CK2) effectively targeting both the CK2 and CK2 catalytic subunits By inhibiting CK2 activity CX-4945 disrupts signaling pathways involved in cell cycle progression transcriptional regulation and cell survival The compound exhibits oral bioavailability and is widely utilized in research focused on tumor biology mechanistic studies of signaling cascades and the functional characterization of protein kinases
Apexbio Technology LLC CX-4945 sodium salt 1309357-15-0 50mg
CX-4945 sodium salt (Silmitasertib sodium salt CAS 1309357-15-0) is a potent and selective inhibitor of casein kinase 2 (CK2) effectively targeting both the CK2 and CK2 catalytic subunits By inhibiting CK2 activity CX-4945 disrupts signaling pathways involved in cell cycle progression transcriptional regulation and cell survival The compound exhibits oral bioavailability and is widely utilized in research focused on tumor biology mechanistic studies of signaling cascades and the functional characterization of protein kinases
Sigma Aldrich Fine Chemicals Biosciences Sodium benzoate BioXtra, >=99.5% | 532-32-1 | MFCD00012463 | 1KG
Sodium benzoate BioXtra, >=99.5% | Purity: >=99.5% | Mol Wt: 144.1 | 532-32-1 | MFCD00012463 | 1KG
Sigma Aldrich Fine Chemicals Biosciences Sodium DL-lactate solution | 72-17-3 | MFCD00065400 | 1L
Sodium DL-lactate solution | Mol Wt: 112.06 | 72-17-3 | MFCD00065400 | 1L
Matrix Scientific TRIFLUOROACETIC ACID POTAS-25G
Trifluoroacetic acid potassium salt, 98%; 25g,C2F3KO2, MFCD00013215, mw 152.12, [2923-16-2]
Cayman Chemical MK886 sodium salt
A potent FLAP antagonist that prevents 5-LO activation in vivo; inhibits LT biosynthesis in leukocytes with an IC50 value of 2.5 nM
Sigma Aldrich Fine Chemicals Biosciences NADP Disodium salt
Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. The NADPH/NADP ratio regulates the intracellular redox potential thereby influencing metabolic reactions in vivo.
Medchemexpress LLC E7766 diammonium salt | 2242635-03-4 | 99.5% | 780.66 | 10 MG
E7766 diammonium salt is a macrocycle-bridged STING agonist with a Kd of 40 nM. It demonstrates potent pan-genotypic and antitumor activities. For research use only, not for sale to patients.
- Macrocycle-bridged STING agonist
- Kd of 40 nM
- Potent pan-genotypic activity
- Potent antitumor activities
- Inhibits four human STING variants (human wild-type, HAQ, AQ, and REF STING proteins) with EC50 values of 1 μM, 2.2 μM, 1.2 μM, and 4.9 μM, respectively
- Shows potent antitumor activity with long-lasting immune memory response in a mouse liver metastatic tumor model
Medchemexpress LLC L 012 sodium salt | 143556-24-5 | 99.9% | 310.67 | 10 MG
L 012 sodium salt is a luminal-based chemiluminescent probe that can detect NADPH oxidase (Nox)-derived superoxide and nitrogen species (reactive oxygen species (ROS) and reactive nitrogen species (RNS)).
- Luminal-based chemiluminescent probe.
- Detects NADPH oxidase (Nox)-derived superoxide and nitrogen species (ROS and RNS).
Medchemexpress LLC L 012 sodium salt | 143556-24-5 | 99.9% | 310.67 | 1 MG
L 012 sodium salt is a luminal-based chemiluminescent probe that can detect NADPH oxidase (Nox)-derived superoxide and nitrogen species (reactive oxygen species (ROS) and reactive nitrogen species (RNS)).
- Detects NADPH oxidase (Nox)-derived superoxide and nitrogen species.
- Identifies reactive oxygen species (ROS) and reactive nitrogen species (RNS).
- Suitable for research applications.
Apexbio Technology LLC Cefoxitin (sodium salt) 33564-30-6 500mg
Cefoxitin sodium salt (CAS 33564-30-6) is a small-molecule inhibitor targeting penicillin-binding proteins (PBPs) It is designed to inhibit PBPs thereby interfering with bacterial cell wall synthesis and peptidoglycan cross-linking Cefoxitin sodium salt exerts its biological activity primarily through inhibition of cell wall synthesis by binding to PBPs In in vitro enzymatic assays Cefoxitin sodium salt demonstrates inhibitory activity against various gram-positive and gram-negative bacteria with previously reported IC50 values in the low micromolar range due to its resistance to certain beta-lactamases including AmpC -lactamases Based on these pharmacological properties Cefoxitin sodium salt holds research potential in investigations of bacterial resistance mechanisms antimicrobial sensitivity profiling and beta-lactamase enzyme kinetics
Apexbio Technology LLC CL 316243 disodium salt 151126-84-0 10mg
CL 316243 disodium salt is a small-molecule agonist targeting the 3-adrenergic receptor It is designed to activate 3 receptors thereby modulating lipolytic and thermogenic pathways predominantly in adipose tissues CL 316243 disodium salt exerts its biological activity by selectively binding to 3-adrenergic receptors leading to enhanced adipocyte-mediated lipid metabolism In experimental rodent models administration of CL 316243 increases insulin sensitivity and reduces obesity-related hyperglycemia by promoting glucose uptake primarily in adipose tissue Based on these pharmacological properties CL 316243 disodium salt holds research potential in the study of 3 receptor-mediated metabolic mechanisms and the exploration of therapeutic strategies for metabolic disorders such as obesity and type 2 diabetes
Apexbio Technology LLC AVE 0991 sodium salt 306288-04-0 2mg
AVE 0991 sodium salt (CAS 306288-04-0) is a synthetic non-peptide agonist of the angiotensin-(1-7) receptor Mas Acting as a functional mimic of angiotensin-(1-7) AVE 0991 competitively binds to endothelial cell membranes with an IC50 of 21 35 nM in bovine aortic endothelial cells In vitro treatment with AVE 0991 promotes nitric oxide release to levels significantly greater than angiotensin-(1-7) In vivo AVE 0991 reduces urine volume and increases urine osmolality in mice effects reversed by angiotensin II antagonists indicating receptor specificity It also inhibits atherogenesis in ApoE knockout mice supporting its application in cardiovascular and renal research
TARGETMOL CHEMICALS INC Danshensu sodium salt 100MG
Also available in 1 mL, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. Danshensu sodium salt (Sodium Danshensu) is sodium salt of danshensu from the widely used Chinese herb Danshen. It can inhibited phenylephrine- and CaCl2-induced vasoconstriction in Ca2+-free medium. Purity 97.04%
Medchemexpress LLC 5-bromouridine 5'-triphosphate sodium salt | 161848-60-8 | MFCD00274403 | 98.0% | 563.04 g/mol | C9H14BrN2O15P3.xNa | 1 MG
5-BrUTP sodium salt is a brominated uridine triphosphate used as a nucleotide analog to label RNA in transcription assays. It can be enzymatically incorporated into nascent RNA during in vitro transcription or cellular labeling, and incorporated BrUTP residues are detected immunologically to quantify or visualize newly synthesized RNA.
- Enables labeling of newly synthesized RNA for transcription analysis.
- Detectable by anti-BrdU antibodies for immunodetection.
- Brominated uridine analog compatible with enzymatic incorporation during transcription.
- Sodium salt form offers improved aqueous solubility for biochemical workflows.
- High purity (98.0%) suitable for sensitive biochemical assays.
- Available in multiple pack sizes to support small- and large-scale experiments.